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Terms of the deal were not disclosed. Through the Buffalo company’s internal research and development, the brain tumor medication has proven successful against cells that are resistant to Temodar, a widely used chemotherapy treatment.
Lastly, in glioblastoma the best standard of care drug, Temodar, increases life by only 10 weeks. If the survival benefit holds longer than 6-9 months in late stage trials, I think it is very likely to become standard of care irrespective of the cost.
It is a small molecule that has shown potent inhibitory activity against a broad panel of brain tumor cell lines, including cells (T98G) that are resistant to Temodar, the most widely used chemotherapy for the treatment of malignant glioma. In a well ...