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Anthra, anthracycline; cont, containing; DD, dose dense; doce, docetaxel; ER−, estrogen receptor negative; ER+, estrogen receptor positive; FAC, fluorouracil (5-FU), doxorubicin and cyclophosphamide regimen; FEC, 5-FU, epirubicin and cyclophosphamide ...
The really good news is that researchers reversed the tumor-friendly effect of the drug, called cyclophosphamide, by inhibiting another cell-communicating protein in the bone marrow, called CCL2. "This work is early and still at the pre-clinical level ...
CYC treatment resulted in a decrease in Ig levels (median; interquartile range IQR) from IgG 12.8 g/L (8.15-15.45) to 9.17 g/L (8.04-9.90) (p = 0.002), IgM 1.05 g/L (0.70-1.41) to 0.83 g/L (0.60-1.17) (p = 0.046) and IgA 2.58 g/L (1.71-3.48) to 1 ...
The Italians are updating their data on R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) vs R-CVP (rituximab, cyclophosphamide, vincristine, and prednisone) vs R-FM (rituximab, fludarabine, and mitoxantrone).
They also stress that mycophenolate mofetil, cyclophosphamide, and methotrexate should be avoided in pregnancy, because they are established human teratogens. Azathioprine, though listed as pregnancy category D indicating teratogenic risk, has been shown ...
Schall, Ph.D., President and CEO, ChemoCentryx. "ANCA vasculitis currently is treated with high-dose corticosteroids and cyclophosphamide, among other noxious treatment regimens in severe cases. Therefore, a novel medicine such as CCX168 could ...
McCauley, the principal investigator on the new study, reveals that the chemotherapy drug called cyclophosphamide is responsible for the ill side effect. On the bright side of things, she believes that a solution to this problem may have already been found.
A majority of the PCPs could not identify any of the late effects associated with cyclophosphamide, paclitaxel, and oxaliplatin. They were most familiar with doxorubicin toxicity, but only because 55% recognized cardiac dysfunction as a late ...
The two regimens are similar: EPOCH contains etoposide, doxorubicin (Adriamycin), vincristine (Oncovin), prednisone, and cyclophosphamide, while CHOP has four of the drugs, but omits etoposide. Barta SK, et al "A pooled analysis of 1,144 ...